Tongkat Ali Extract Powder 100:1, 200:1 TLC, Eurycomanone 1%, 2%, 3%, 5% HPLC

Tongkat Ali Extract Powder 100:1, 200:1 TLC, Eurycomanone 1%, 2%, 3%, 5% HPLC

Eurycomanone is the most active ingredient of tongkat ali extract powder, which can improve male sexual function, as well as have anti-cancer and anti malaria effects. In addition, it has various pharmacological effects such as lowering blood sugar, blood pressure, lowering uric acid levels in hyperuricemia model rats, and alleviating pathological damage to kidney tissue, especially in improving male sexual function, which has attracted widespread attention from the scientific community.

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Tongkat Ali Extract Powder 100:1, 200:1 TLC;
Eurycomanone 1%, 2%, 3%, 5% HPLC


tongkat ali extract
Plant origin:
Dried root of plant Eurycoma longifolia Jack 

Raw materials origin: Indonesia, Malaysia
Components: The chemical components isolated from tongkat ali are mainly diterpenes with a quassinoid skeleton and canthin-6-one alkaloids, such as eurycomaoside, eurycolactone, eurycomalatone, eurycomanone, and pasakbumin-B. In addition, it also contains biphenyl lignin, squalene derivatives, etc.
Specification: Eurycomanone 1%, 2%, 3%. 5% HPLC, 100:1, 200:1 TLC
CAS No.: 84633-29-4 for (eurycomanone)
Molecular formula: 408.39916 g/mol (eurycomanone)
Molecular structure:Solvent used: Ethanol
Solubility: Soluble in both ethanol and water
Product characteristics: Light brownish to brownish fine powder.
Particle size: 95% pass 80 mesh size
Main use: Mainly used for regulating endocrine function, enhancing immunity, treating gout and prostatitis, etc. Its unique chemical composition makes it occupy an important position in traditional medicine and is known as one of the most precious applied plant medicines in Southeast Asia.
Packaging: 1kg/bag is packaged in carton boxes or fiber drums, with double layered self-sealing bags inside or can be packaged according to customer needs.Pine-pollen-extract packing
Storage: This product should be sealed and kept away from light, and stored in a dry, cool, well ventilated place.
Shelf life: 24 months from the date of production.
Minimum order quantity: 1 kilogram.
Production lead time: About 3-5 working days after confirming receipt of payment.

Production Process of Tongkat Ali Extract

Raw material cleaning — raw material crushing — purified water extraction — concentration — spray drying — crushing — sieving — mixing — finished product test and packing

1.Raw material preparation: Select high-quality tongkat ali raw materials, clean them, and carry out impurity removal and crushing treatment to ensure the purity of the raw materials and their suitability for subsequent extraction. Dried Tongkat Ali raw materials is crused to a particle size of 80-120 mesh for next step.

2. Extraction: Extract the crushed tongkat ali raw material and extract it under controlled temperature and pressure conditions to release the active ingredients. Take 500kg of crushed powder and perform continuous countercurrent ultrasonic extraction. Add purified water equivalent to 10 times the weight of the raw material, ultrasonic extraction time is 30min, temperature is 20 ℃, and ultrasonic frequency is 30KHZ to obtain the extraction solution.

3.Concentrate to extractum: Pump the filtrate from the storage tank into a single effect concentrator for concentration, control the vacuum at 0.06-0.08 megapascals, and concentrate at a temperature of 60-80 degrees Celsius. Concentrate the filtrate to a relative density until it meets the powder spraying requirements.

Centrifuge the extracted solution obtained previous step through a tubular centrifuge, pass the centrifuged solution through an ultrafiltration membrane with a molecular weight of 10000, and then transfer it to a membrane concentration device for concentration to a Brix value of 9.6. The weight of the concentrated solution obtained is 86kg.

4.Spray drying: Transfer the concentrated solution obtained to a mixing tank, add 14.48kg of alpha cyclodextrin, stir and homogenize at room temperature for 20 minutes to obtain a homogeneous solution; The weight ratio of the encapsulating agent to the solute in the concentrated solution is 2:1.

Carry out spray drying of the homogeneous solution obtained to obtain 20.98kg of Tongkat Ali extract powder. The total weight content of ketone and epoxy ketone in the powder was determined to be 6.44% by HPLC method, and the active ingredient transfer rate was 96.51wt%. The product has a low bitterness.

5.Crushing and sieving: After drying, the powder is crushed, refined, and sieved to remove caking and ensure that the powder mesh is qualified.

6.Product mixing: Mix different batches of extracts as needed to ensure product uniformity.

7. Test and Packing: Testing the physical and chemical indicators of the product, and pack qualified products in bags weighing 25KG, label them, and store them in the warehouse.

HPLC Chromatogram of Tongkat Ali Extract 1% Eurycomanone

HPLC Chromatogram of Tongkat Ali Extract 1% Eurycomanon

Certificate of Analysis of Tongkat Ali Extract 1% Eurycomanone HPLC

COA of Tongkat ali extract

Pharmacological effects of Tongkat Ali Extract Powder


1.Enhance renal function and improve sexual function

Traditional Chinese medicine theory believes that “the kidney is the foundation of innate development”, which is responsible for the growth and development, reproduction, body liquid metabolism, and absorption of “qi” in the human body. Tongkat ali extract, through its unique biochemical composition, promotes the secretion of more hormones, male hormones, progesterone, etc. in the human body, which can regulate the endocrine system, balance the body’s yin and yang, enhance blood circulation and metabolism, increase kidney power, and prolong the life of the kidneys, making people healthier and to live longer.

Tongkat ali extract can promote the production of more testosterone in the human body, with an increase of up to 440%. Human trials have shown that DHEA (a male hormone) levels increased from 26% after one week of taking Donggai Ali to 47% after three weeks, while SHBG (a protein sphere that inhibits male hormones) levels decreased by 36% after one week and 66% after three weeks. The result is that when SHBG decreases, the “free testosterone index” of the vast majority of participants increases. The increase in the “free testosterone index” indicates that Dongge Ali has a biological promoting (rather than pharmacological) effect on the production of male hormones. The level of “free testosterone index” in human blood determines the health status and sexual ability level of men.

Tongkat ali extract can promote the hypothalamus and pituitary gland to send signals to the testosterone secretion system, causing it to produce more testosterone. This endogenous testosterone is different from oral testosterone. Artificially synthesized testosterone (synthetic steroids) can supplement the body’s testosterone, but it can seriously affect male sexual characteristics, causing symptoms such as testicular shrinkage.

When testosterone levels rise in the human body, sex hormones send signals to the body to reduce or stop their own testosterone production, which is called a ‘negative response’. Tongkat ali extract can intercept these “negative reaction” signals, thereby causing the body to continuously produce high levels of testosterone. Because the production of testosterone is at full speed, the penis and testicles will become larger in volume. More research has further demonstrated the principle of Tongkat ali extract as an effective and unique sex stimulant.

2.The effect on gout

Dr. Kamal Ketuly, a British herbalist, and pharmacologists from the Malaysian Academy of Sciences analyzed the chemical composition of tongkat ali in the laboratory of Rainforest Herbal Company and found that it contains a natural phytochemical called probenecid, which can effectively regulate human secretion, inhibit uric acid synthesis, and prevent uric acid from precipitating in the form of sodium salt crystals in human joints, cartilage, soft tissues, and other parts. This surprising discovery led them to infer that tongkat ali has a therapeutic effect on gout. Subsequently, scientists conducted a large number of experiments to prove that tongkat Ali indeed has significant therapeutic effects on gout.

3.Anti cancer function

Researchers at the University of Tokyo School of Medicine in Japan have isolated anti-cancer substances from tongkat ali. They have proved through experiments that beta carbon extracted from tongkat ali has a strong therapeutic effect on lung cancer and breast cancer.

According to Abdul Razak Mohd Ali, the director of the Malaysian Forest Research Institute, the chemical components in Tongkat Ali are more effective than existing anti-cancer drugs. In addition, other experiments have also shown that the chemical composition of Auassinoid contained in Tongkat Ali can have anti-tumor and anti fever effects.

4.Function of promoting fertility

Research has found that Tongkat Ali can improve sperm quality, increase sperm quantity, size, and movement speed. In the laboratory experiment on white mice, the volume of offspring produced by female mice taking Tongkat Ali was twice that of offspring produced by female mice not taking Tongkat Ali. Researchers speculate that this may be caused by female mouse egg division, twins, and multiple ovulation. Their conclusion from the experiment is that stronger fertility is entirely the result of increased sperm quantity and quality. In addition, the effect of Tongkat Ali on improving fertility is also very significant. In animal experiments, male offspring showed a threefold increase compared to female offspring.

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